25 results
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... - Bacterial: Sepsis ... Microangiopathy: DIC ... #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... #rheumatology #diagnosis ... #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... intravascular coagulation (DIC ... usually IgG) (e.g. lupus ... #differential # ... diagnosis #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... of SLE versus DIL ... Positive in 60-80% of cases ... Erythematosus #Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
history of trauma, sepsis ... organ damage Clinical ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... fulminans - DIC ... Autoimmune Vasculitis (lupus ... #Causes #dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Seizure disorders, Aseptic ... autoantibodies that will cause ... permeability Diagnosis ... #management #treatment
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
for example, in sepsis ... vasodilatation produces ... shock is often clinically ... #Diagnosis #CriticalCare ... #Shock #Differential
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
acid metabolism products ... = nonspecific (nausea ... rapidly develops (DIC ... infiltration) Differential ... Diagnosis: Viral
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... inflammation persist → DIC ... the key to the diagnosis ... Canimorsus #Skin #Rash #dermatology ... #clinical #photo