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diagnosis hematology algorithm classification extravascular hemolytic intravascular jaundice bilirubinemia comparison conjugated dermatology hellp hepatitis hodgkins injury lfts liver liverenzymes management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... uremic syndrome (HUS ... e.g. lupus, CLL, lymphoma ... #differential # ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... anemia • ... MAHA (TTP, DIC, HUS ... #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • MAHA: TTP, HUS ... #Anemia #Differential ... classification #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Pregnancy - TTP/HUS ... of Pregnancy (AFLP ... defects. 1) HELLP (Hemolysis ... child * Severe cases ... #diagnosis #table
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... • Pregnancy - AFLP ... Drugs • TPN • Sepsis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Production • Hemolysis ... Hepatic Uptake • Sepsis ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Algorithm Vascular Causes ... cell lung CA, lymphoma ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
persons • It has ... Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... Immunohistochemical studies (to differentiate
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
production (eg, hemolytic ... anemias, hemolytic ... biliary cirrhosis, sepsis ... , sarcoidosis, lymphomas ... #unconjugated #differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... disease - DIC/TTP/HUS ... - Hemolytic ... anemia - Splenomegaly ... : • DIC, TTP/HUS
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