11 results
diagnosis hematology causes management algorithm anemia blood extravascular hemolytic microangiopathy product reactions thrombocytopenia thrombotic classification coagulation comparison dermatology dic disseminated
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
thrombocytopenic purpura ... (TTP), Hemolytic ... uremic syndrome (HUS ... #Hemolytic #Intravascular ... #Causes #differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... • MAHA (TTP ... , DIC, HUS) ... Differential #Diagnosis ... Algorithm #Causes #Hematology
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
VS HUS Big picture ... Often hard to differentiate ... thrombocytopenic #purpura ... Comparison #Diagnosis #Table ... #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis Table ... Thrombocytopenic Purpura ... (TTP) • Shiga ... Microangiopathy #TMA #hematology ... #differential #
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombocytopenic purpura ... /hemolytic uremic ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /HUS - Hemolytic ... Defects: • DIC, TTP ... /HUS • Anticoagulants ... #Differential #
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... IVIG infusion Intravascular ... Causes: • MAHA: TTP ... , HUS, DIC, HELLP
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Thrombocytopenic Purpura ... reflection of intravascular ... WBC count and differential ... impairment #TTP
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... history of trauma, sepsis ... Petechiae • Purpura ... DDX: • TMA’s (HUS ... /TTP/DITMA) -
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Post Transfusion Purpura ... (PTP): Occurs 7 ... Causes purpura & ... Occurs between 0-6 hrs ... Can lead to sepsis
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