11 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
the peripheral blood ... TTP/HUS indicates ... thrombocytopenic purpura/hemolytic ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... - MAHA: TTP, HUS ... - Peripheral Blood ... #Differential # ... Diagnosis #hematology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Production • Hemolysis ... Hepatic Uptake • Sepsis ... Post-Hepatic - Usually has ... Algorithm #Causes #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Drugs • TPN • Sepsis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Differential #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... ALT or AST): • US ... Drugs, Infection, Sepsis ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... intestines, White blood ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Occurs between 0-6 hrs ... Can lead to sepsis ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Hemolysis on labs ... Occurs between 0-6 hrs ... Can lead to sepsis ... Transfusions #diagnosis #management ... #hematology #reactions
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... DDX: • TMA’s (HUS ... - MAHA: TTP/HUS ... causes #treatment #management ... #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Diagnosis and Management ... eosinophilia with blood ... eosinophilia #diagnosis #hematology ... #differential # ... management #eosinophils