13 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... fraction < 20% Differential ... Complications: MAS ... #diagnosis #management ... #treatment #rheumatology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Distributive: Sepsis ... , Severe Valve Disease ... Sophia Hayes MD ... #Diagnosis #criticalcare ... algorithm #treatment #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Activation Syndrome (MAS ... manifestation of MAS ... Plasma exchange #MAS ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
chemotherapy for low-risk disease ... Lauren Banaszak, MD ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Seizure disorders, Aseptic ... Cerebrovascular Disease ... (for secondary APS ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
initiation • Differential ... Diagnosis: Infection (sepsis ... coagulopathy, RRT/IMV as ... APML #diagnosis #management ... #hematology #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
brainstem lesions, aseptic ... ) Differential Diagnosis ... Reactive Arthritis, AS ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Beta-Agonists, ↑ work ... Malaria, Late Sepsis ... infographic by Nick Mark MD ... #Diagnosis #criticalcare
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... , APLA, PAC • Aseptic ... La, anti-Jo-1, SCL ... (C3 and C4) • ds-DNA
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... Workup: • Complete ... blood count with differential ... #oncology