13 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... #Liver #Injury ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... • Infectious: Sepsis ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology ... gastroenterology #management
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Distributive: Sepsis ... Insufficiency, Liver ... Medications, Spinal Cord Injury ... #criticalcare #algorithm ... #treatment #management
Mild-to-Moderate Ulcerative Colitis - Management Algorithm
Curcumin:
 • Natural phytochemical from turmeric
 • 2g/day divided in 2-3
Ulcerative Colitis - Management ... Potential GI SE, liver ... injury, inhibit ... Nissle • VSL#3: ↑ clinical ... Budesonide to induce
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... hypoperfusion - toxic-induced ... or renal injury ... Injury: • Reduced ... Acidosis #Elevation #Differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... - Alcohol-induced ... the spleen or liver ... NonHodgkins #comparison #oncology ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
endothelial damage • Induce ... initiation • Differential ... Diagnosis: Infection (sepsis ... APML #diagnosis #management ... #hematology #oncology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... (→ 3-1) Drug induced ... Traumatic brain injury ... #Hyperthermia #Differential ... Checklist #Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
history of trauma, sepsis ... organ damage Clinical ... DIC • Severe Liver ... causes #treatment #management ... #hematology