13 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... Injury #Medications ... #Differential # ... #LiverInjury #Hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... or symptoms of liver ... #differential # ... gastroenterology #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... (>1000): • DILI ... injury) • Ischemic ... #Tests #LFTs #Differential ... #Diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... • Iatrogenic: DILI ... #differential # ... diagnosis #algorithm #hepatology
Shock Classification and Differential Diagnosis
SHOCK
 • MAP <65, SBP <90, drop in SBP > 40
 •
and Differential ... / Low SVR • Sepsis ... Insufficiency, Liver ... Medications, Spinal Cord Injury ... Diagnosis #Types #criticalcare
Shock Types and Classification
DISTRIBUTIVE 66%
 • Sepsis/SIRS, anaphylaxis, adrenal insufficiency, liver failure, toxins, spinal/neurogenic
 • Warm
Shock Types and Classification ... DISTRIBUTIVE 66% • Sepsis ... insufficiency, liver ... #diagnosis #differential ... #criticalcare
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Injury - Differential ... • Infectious: Sepsis ... #Injury #Differential ... Acute #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
injury < 26 weeks ... Unconjugated Bili ... > 90% of Total Bili ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... change disease • Hematologic ... Treatment Related • Sepsis ... Cancer #Oncology #Differential ... #Diagnosis #Classification
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Distributive: Sepsis ... Insufficiency, Liver ... Medications, Spinal Cord Injury ... #Diagnosis #criticalcare