29 results
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
reactions, hematoma, pulmonary ... Crigler-Najjar syndrome ... , Rotor syndrome ... biliary cirrhosis, sepsis ... #unconjugated #differential
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Lymphoproliferative disorders (e.g ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
Causes of Peripheral Edema - Differential Diagnosis
Increased Hydrostatic Pressure
 • Volume Expansion: Kidney failure, Pregnancy, Medication
Peripheral Edema - Differential ... Heart failure, Pulmonary ... Cirrhosis, Nephrotic syndrome ... Permeability: Sepsis ... Peripheral #Edema #Differential
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Edema - Differential ... level <100 pg/ml EKG ... respiratory distress syndrome ... Gram negative sepsis ... #diagnosis #cardiology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Distributive: Sepsis ... • Obstructive: Pulmonary ... Abdominal compartment syndrome ... Dehydration Shock Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Eclampsia, Infection/Sepsis ... Reversible course Differential ... • EEG: With persistent ... epilepticus Treatment ... underlying cause • Treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Seizure disorders, Aseptic ... Lumbar Puncture, EEG ... Treatment: ... CNS #neurology #rheumatology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... anaesthesia • Sepsis ... • Serotonin syndrome ... Anticholinergic syndrome ... #Hyperthermia #Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... initiation • Differential ... Renal Failure Treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
underlying disease (eg ... • Infection (eg ... brucellosis) • Sepsis ... Treatment: • Corticosteroids ... #Rheumatology