18 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... edgarvlermamd #Potassium ... #Binding #KBinders ... Kayexelate #Comparison #Table ... #HyperKalemia #Nephrology
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Phosphate Binders ... and metal-free binder ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... cyclosilicate #Potassium ... #Binders #Management ... #pharmacology #table ... #comparison #nephrology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Decreased renal potassium ... Drugs Increased potassium ... (oral/iv) • Potassium-rich ... • Tumor lysis/hemolysis ... Diagnosis #algorithm #nephrology
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
Phosphate binders ... since they are not able ... aluminum-based phosphate binder ... calcium-based phosphate binders ... Only* #CKD #Nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... nonspecifically binds ... of aspiration #Potassium ... #pharmacology #table ... #comparison #binders
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Chlorthalidone POTASSIUM-SPARING ... Pharmacology #summary #table ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
venipuncture • Hemolysis ... • Recent IV potassium ... cell lysis: - Hemolysis ... diagnosis #causes #potassium ... #high #nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... edgarvlermamd - Nephrology ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology #Nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
venipuncture • Hemolysis ... • Recent IV potassium ... cell lysis: - Hemolysis ... diagnosis #causes #potassium ... #high #nephrology