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treatment algorithm gastroenterology hepatitis liver aclf ah aih alcoholic apml autoimmune blood causes chronic cirrhosis coagulation criteria dic differential differentiation
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... symptoms of liver disease ... Calculate R-Value ... gastroenterology #hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
Clinical diagnosis ... >1.5, and both values ... Possible drug-induced ... Uncertain alcohol use assessment ... Hepatitis #AH #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... underlying liver disease ... Hepatitis (AAH) Drug-Induced ... Failure #Cirrhosis #Hepatology ... #diagnosis
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
Clinical Diagnosis ... >1.5, and both values ... Possible drug-induced ... Uncertain alcohol use assessment ... #Hepatology #AIH
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced ... → Calculate 4T score ... • If 4T score ... #HIT #Heparin #Induced ... #Hematology #HemeOnc
Non-alcoholic fatty liver disease algorithm. For those patients with NAFLD or liver disease of unknown aetiology,
Initial assessment ... NAFLD fibrosis score ... with values <1.3 ... algorithm #Referral #Management ... #Hepatology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... severity Treatment - Acute ... Avoid meds that ... though safety assessment ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
endothelial damage • Induce ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... organ dysfuxtion, ICU ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... • Severe Liver Disease ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Transfusion Related Acute ... Borrellia (Lyme disease ... #Transfusions #diagnosis ... #management #hematology
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