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diagnosis nephrology differential causes algorithm management hypokalemia metabolic low treatment gitelman hyperkalemia workup hyponatremia hypophosphatemia rheumatology signs symptoms acidosis chloride
Causes of Metabolic Alkalosis - Differential Diagnosis Chloride depletion syndromes • Gastrointestinal losses -
Causes of Metabolic Alkalosis ... chloridorrhea - High-volume ... villous adenomas • Renal ... • Severe potassium ... #Metabolic #Alkalosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... Diuretics (late) • High ... hyperaldosteronism • High ... PRA: Renal artery ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... Diuretics (late) • High ... hyperaldosteronism • High ... PRA: Renal artery ... Diagnosis #Algorithm #Nephrology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Algorithm Extra-renal ... loss (Diarrhea) Renal ... • HTN, High Aldosterone ... Algorithm #causes #potassium ... #low #nephrology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Transcellular Shift: • Alkalosis ... • Refeeding syndrome ... Medications Renal ... Losses Non-renal ... #low #potassium
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
potassium excretion ... • Acute renal ... Normal, Renin High ... hypoplasia Aldosterone high ... Diagnosis #algorithm #nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... suggests extra-renal ... urinary losses: • High ... - Metabolic Alkalosis ... #nephrology #low
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm GI Losses - Gastric • Vomiting • NG suction GI
Causes of Metabolic Alkalosis ... Chloridorrhea Renal ... • Penicillins Renal ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... to diarrhea, a high ... of sodium and potassium ... urine #Algorithm #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Causes of Metabolic Alkalosis ... diuretics after renal ... generally indicates a renal ... other • Severe potassium ... Diagnosis #Causes #nephrology
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