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diagnosis differential symptoms peds neurology nutrition geriatrics management psychiatry algorithm bulimianervosa cardiology deficiency dementia endocrinology features genetics manifestations ophthalmology physicalexam
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer’s Disease ... mutations - Down syndrome ... / Symptoms / Complications ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. Affects
Kawasaki Disease ... lethal cardiac complications ... #Kawasaki #Disease ... #Features #Signs ... Diagnosis #Peds #Pediatrics
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... Dose-dependent tremor, ataxia ... dizziness, diplopia, ataxia ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... /Complications: ... #genetics #pathophysiology ... #peds #pediatrics
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Risk Factors and Signs ... diarrhoea, Short bowel syndrome ... , Malnutrition Signs ... Optic neuropathy, Ataxia ... Deficiency #diagnosis #signs
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Vitamin D - Bone disease ... • Thiamine - Nausea ... dysfunction, gait ataxia ... ), Korsakoff syndrome ... sensory neuropathy, ataxia
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
Refeeding Syndrome ... Risk of Refeeding Syndrome ... CNS: Tremors, Ataxia ... #diagnosis #pathophysiology ... #symptoms #signs
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... lumbar spine Signs ... / Symptoms / Complications ... #MSK #pathophysiology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... mainly AQP4-lgG disease ... (AQP4-lgG disease ... pain • Extra-CNS complications ... neurology #symptoms #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Fits, Hemiplegia, Ataxia ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs
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