17 results
Stroke and bleeding risk stratification with the CHADS2-VASc and HAS-BLED schemas

#Diagnosis #Hematology #CHADS2 #CHADS2VASc #HASBLED #Comparison
Stroke and bleeding ... risk stratification ... #Diagnosis #Hematology ... CHADS2VASc #HASBLED #Comparison ... #Score #Risk #Stroke
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
Bleeding risk calculators ... risk tools have ... validated for VTE treatment ... risk • No RCTs ... Anticoagulation #Factors #Hematology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
dysfunction (e.g. gait ... ataxia - usually ... Any risk factor ... Anorexia nervosa Treatment ... Encephalopathy • A prompt treatment
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
patients at high risk ... of bleeding. ... risk during follow-up ... also balance the risk ... Anticoagulation #Management #Hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
scores for stroke risk ... and bleed risk ... S Stroke 1 B Bleeding ... CHADS2VASc #HASBLED #Comparison ... AFib #Diagnosis #Hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Classify severity Treatment ... by a hemophilia treatment ... risk ... Diagnosis #Management #treatment ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings: • Bleeding ... thrombopoietin deficiency ... Treatment: ... diagnosis #causes #treatment ... #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
transfused patientsl • Risk ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
prematurely • risk ... • Vitamin C deficiency ... Pernicious anemia/B12 deficiency ... ) - Waddling gait ... Hyophosphatasia #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Attempt if high risk ... effusions, weight gain ... Renal Failure Treatment ... diagnosis #management #hematology