26 results
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
B1 (Thiamine) Deficiency ... dysfunction (e.g. gait ... ataxia - usually ... Anorexia nervosa Treatment ... Encephalopathy • A prompt treatment
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Thiamine (B1) Deficiency ... dysfunction - Dietary deficiency ... dysfunction and gait ... ataxia is only ... #Thiamine #B1 #Deficiency
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
Syndrome - Thiamine Deficiency ... thiamine (vitamin B1) deficiency ... of confusion, ataxia ... (broad-based gait ... #B1 #thiamine #deficiency
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Non malignant hematologic ... effect following treatment ... states • Non-hematologic ... malignancy • Iron deficiency ... Algorithm #Causes #Hematology
Causes of Gait Disturbance - Differential Diagnosis Algorithm
Sporadic
 • Vascular
 • Infection
 • Toxic
 • Nutrition
Causes of Gait Disturbance ... • Friedrich's Ataxia ... Childhood Catalytic Deficiency ... Childhood Catalytic Deficiency ... Niemann-Pick Disease #Gait
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... severe, ADAMTS13 deficiency ... HUS) Treatment ... #rheumatology # ... hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... Acute hemolysis, deficiency ... Rebound effect from treatment ... Diagnosis #Algorithm #hematology
Wernicke Encephalopathy - Triad

Encephalopathy 
 • Disorientation 
 • Indifference 
 • Inattentiveness 
Ocular motor dysfunction
gaze palsies Ataxia ... • Gait • ... Neurology #Thiamine #Deficiency
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
testing and expedite treatment ... leukodystrophy w/ deficiency ... failure, cerebellar ataxia
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Signs of Copper Deficiency ... dental fixatives, Treatment ... Optic neuropathy, Ataxia ... drkeithsiau #Copper #Deficiency