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Initial Clinical and Laboratory Data Base for Defining Major Syndromes in Nephrology

#Major #Syndromes #Nephrology #Diagnosis #Workup
Defining Major Syndromes ... Nephrology #Major #Syndromes ... #Nephrology #Diagnosis ... #Workup #Differential ... #Table
Gerstmann Syndrome
1) Finger agnosia - Inability to name their own fingers, affecting both sides
2) Right-left confusion
Gerstmann Syndrome ... 1) Finger agnosia ... name their own fingers ... patient is still able ... #neurology #diagnosis
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
- Differential Diagnosis ... /uL Initial Workup ... : CBC with diff, ... #Algorithm #hematology ... #workup
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... hemolytic uremic syndrome ... thrombocytopenia, Hematology ... 2012, p 193 #Diagnosis
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... HLH syndrome 5. ... #Pancytopenia #Workup ... #Algorithm #Hematology
Age-Focused Initial Evaluation for Pyoderma Gangrenosum 

All Patients: 
 - A thorough history and physical examination
mycobacterial) - CBC ... #Gangrenosum #Workup ... Evaluation #Age #Dermatology ... #Diagnosis
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... with erosions • CBC ... SCVMCMed #DRESS #Syndrome ... TEN #comparison #table ... #dermatology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Gitelman syndrome ... - Hungry bones syndrome ... #Differential #Diagnosis ... Low #Magnesium #Table ... Classification #Causes #Workup
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
- No other workup ... cancer screening, CBC ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... Catastrophic APLS BCM ... #differential #diagnosis ... #hematology #hemolysis