18 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Coagulation Failure Infections ... Drug-Induced Liver Injury
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... Myelofibrosis Infectious ... : • Acute or Chronic ... disorders • Celiac disease ... effect following treatment
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Differential #Diagnosis #Algorithm ... #hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Parenchyma • Infectious ... Hepatitis, TPN • Infectious ... Sophia_Hayes_MD #Liver #Injury ... #algorithm #hepatology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
associated with the BCR-ABL1 ... translocation • Acute ... Colitis and Crohn’s Disease ... Irradiation • Cirrhosis ... Diagnosis #causes #hematology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... LC deposition disease ... Minimal change disease ... • Hematologic ... malignancies Treatment
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Differential Diagnosis Algorithm ... - Oncotic • Cirrhosis ... Urinothorax Exudate - Infectious ... • Postcardiac injury ... #Hepatology #causes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • Infectious: HAV ... hepatitis: < 1 • Cirrhosis ... #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
• HIV/HCV co-infection ... or fibrosis • Cirrhosis ... HBV infection with ... severe liver injury ... > 3 mg/dL) or acute
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... Hepatocellular: Viral infections ... Alcohol-related liver disease ... dechallenge • Acute ... #hepatology