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diagnosis differential management nephrology causes hematuria urine aki algorithm kidney hematology infectiousdiseases microscopy cardiology classification clinical endocarditis kidneyinjury laboratory lactate
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
tubular cells - Acute ... tubular injury ... - Renal infection ... renal disease ... tubular injury
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Urinalysis >3 RBCs ... repeat testing • Acute ... proteinuria, RBC casts ... for renal biopsy ... #blood #urine
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Kidney Injury ( ... • Sepsis • Blood ... • Inflammatory disease ... • Infection ... #Kidney #Injury
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Disease Associations ... are seen in acute ... Red blood cell ... Urinary tract infections ... tubulointerstitial nephritis, renal
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
Acute Kidney Injury ... Immune-complex disease ... Immune-mediated, Infection-mediated ... Bilateral ureteral disease ... #Kidney #Injury
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... Kidney Injury ( ... at least 50% Renal ... Epithelial cell casts ... allopurinol, PPI) • Infections
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... thromboembolism, renal ... • Primary GNs: Disease ... Post-infectious ... Tubular Injury/
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... Light chain (LC) cast ... LC deposition disease ... gammopathy of renal ... malignancies Treatment
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
urine • 1ml blood ... Immune mediated injury ... hematuria: - RBC casts ... #nephrology #renal ... #urine #blood
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Statins - ETOH - Infection ... UA positive for blood ... Cast formation: ... disease 2. ... #nephrology
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