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diagnosis differential hematology nephrology oncology management syndrome aki algorithm anemia basophilia basophils calculation causes chronic classification dehydrogenase dermatology elevated encephalopathy
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... ALL (Acute Lymphoblastic ... extramedullary disease ... Philadelphia - BCR-ABL ... lymphoid organs When Cancer
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Kidney Injury ( ... • Sepsis • Blood ... • Inflammatory disease ... #Kidney #Injury ... #Differential #Nephrology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... cells can indicate disease ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... ’s lymphoma or acute
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... LC deposition disease ... Minimal change disease ... malignancies Treatment ... #Kidney #Injury
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... with the BCR-ABL1 ... translocation • Acute ... thrombocythemia • Acute ... Colitis and Crohn’s Disease
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
carcinoma., Prostate cancer ... , Busulfan • Disease ... #blood #urine # ... management #treatment ... #nephrology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
concentrations in: RBCs ... muscle, liver, and kidney ... of red blood cell ... : • Early acute ... Lymphomas • Leukemias
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Chronic kidney ... disease, Hypothyroidism ... infiltration (e.g. cancer ... Index > 3: • Acute ... defects (e.g. sickle cell
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... with systemic disease ... general feeling of ill ... neutrophils in the blood ... Treatment: - Systemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... C4) • ds-DNA: Kidney ... Hodgkin lymphoma and leukemia ... • Lung cancer ... • Cervical cancer
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