16 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... underlying liver disease ... Circulation Failure ... Kidney Failure ... Infections Alcohol-Associated
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... LC deposition disease ... • Hematologic ... malignancies Treatment ... #Kidney #Injury
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Torsemide) • Acute ... disease • Liddle ... hyperaldosteronism • Acute ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
deficiencies: Chronic kidney ... disease, Hypothyroidism ... • Bone marrow failure ... Index > 3: • Acute ... Production #Index #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Failure ( ... of cholestatic disease ... ALT Ratios: • Alcoholic ... liver disease: ... #differential #Hepatology
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
as a marker of kidney ... Diet in Renal Disease ... as are seen in acute ... renal failure, ... #Diagnosis #Nephrology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... lesions, meninges, kidneys ... hypergammaglobulinemia, ↑ acute ... maintenance with GCs ... #rheumatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... liver disease, ... dechallenge • Acute
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... : - Acute kidney ... - Concomitant diseases ... HCV, DILI, HCC, acute ... - Multiorgan failure
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Ketoacidosis: Diabetic, Alcoholic ... oxoproline) • Renal failure ... (acute and chronic ... Chronic progressive kidney ... disease Ill.