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diagnosis hepatology liver algorithm differential hepatitis management nephrology aclf aih aki alcoholic autoimmune cancer chemistry cirrhosis classification cll diuresis diuretics
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Kidney Failure ... (DILI) Viral Hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... non-essential drug/HDS treatments ... Alcohol-related liver disease ... dechallenge • Acute ... or chronic atypical
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... • Hematologic ... malignancies Treatment ... #Kidney #Injury ... #AKI #Cancer #Oncology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... • Iatrogenic: DILI ... > 2 • NASH, Chronic ... > 3 • Chronic ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Failure ( ... of cholestatic disease ... Alcoholic liver disease ... > 2 • NASH, Chronic ... > 3 • Chronic
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
kidney disease, ... kidney disease, ... kidney disease ... kidney disease ... Tolvaptan) • Treatment
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
: - Acute kidney ... injury with serum ... - Concomitant diseases ... HCV, DILI, HCC, ... - Multiorgan failure
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... to acute liver ... failure ... - Symptoms of chronic ... pattern of liver injury
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... microglobulin Treatment ... • Bone marrow failure ... ’s lymphoma or acute ... #hematology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
advanced liver disease ... hepatitis, or acute ... liver failure ... Treatment Overview ... #Nephrology #Diagnosis
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