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Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Kidney Injury ( ... perfusion: • Cardiac failure ... • Inflammatory disease ... #Kidney #Injury ... #Differential #Nephrology
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
Causes of acute ... kidney injury (AKI ... and interstitial disease ... Diagnosis #AKI #Acute ... Causes #Sites #Nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... Immune-complex disease ... Bilateral ureteral disease ... ASanchez_PS #AKI #Acute ... #Kidney #Injury
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... HEMODYNAMIC • Cardiac failure ... thromboembolism, renal ... tumors INTRINSINC RENAL ... • Primary GNs: Disease
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... Dehydration • Heart failure ... syndrome) • Liver failure ... #Kidney #Injury ... Classification #diagnosis #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... Torsemide) • Acute ... hyperaldosteronism • Acute ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology
Glomerular Diseases - Spectrum
 - Insidious vs Acute
 - Nephritic (hypertension, hematuria, renal failure) vs Nephrotic
Glomerular Diseases ... - Insidious vs Acute ... hypertension, hematuria, renal ... failure) vs Nephrotic ... differential #diagnosis #nephrology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... LC deposition disease ... gammopathy of renal ... malignancies Treatment ... #Kidney #Injury
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Kidney Failure ... EmoryGastroHep #ACLF #Acute
Cardiorenal Syndrome (CRS) Types
 • Type 1 - Acute CRS: Alteration of renal perfusion is the
Types • Type 1 - Acute ... congestive heart failure ... effects • Type 3 - Acute ... RCS: Salt and water ... Types #cardiology #nephrology