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diagnosis differential nephrology causes hepatology management oncology rheumatology aki alkaline basophils cancer classification dehydrogenase diuresis diuretics elevated excretion hepatorenal hrs
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... attack Is It A Real ... translocation • Acute ... Colitis and Crohn’s Disease ... Diagnosis #causes #hematology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... LC deposition disease ... gammopathy of renal ... • Hematologic ... malignancies Treatment
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... Torsemide) • Acute ... hyperaldosteronism • Acute ... Prevention of blood ... Tolvaptan) • Treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL (Acute Lymphoblastic ... extramedullary disease ... Philadelphia - BCR-ABL ... eosinophilia, basophilia ... #Leukemia #Hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
tubule of the kidney ... Malnutrition • Wilson's disease ... deficiency • blood ... respiratory failure • Neurologic ... : - Renal failure
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... pancreas, biliary, renal ... lesions, meninges, kidneys ... hypergammaglobulinemia, ↑ acute ... #rheumatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
concentrations in: RBCs ... muscle, liver, and kidney ... deficiency of red blood ... hepatitis • Acute ... 94 and 84% Renal
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
UA positive for blood ... nephrotoxicity to kidney ... Treatment of underlying ... disease 2. ... #nephrology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
advanced liver disease ... hepatitis, or acute ... casts, protein, or blood ... Treatment Overview ... #Nephrology #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... pulses, bruits, or blood ... affects the skin, neurologic ... musculoskeletal systems • Kidneys ... , Elevated AST ALT
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