11 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... #Algorithm #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... during an allergic reaction ... associated with the BCR-ABL1 ... translocation • Acute ... #causes #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Meningitis, Myelopathy, Encephalopathy ... permeability Diagnosis ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... : 33% • Treatment ... At least 3 of (Acute ... : No • Treatment ... #hematology #diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... Transfusion Related Acute ... RBCs (stored at ... #Transfusion #diagnosis ... #management #hematology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
with response to treatment ... hypergammaglobulinemia, ↑ acute ... IgG4+ cells" Treatment ... maintenance with GCs ... #rheumatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Transfusion Related Acute ... RBCs (stored at ... #Transfusions #diagnosis ... #management #hematology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
A reaction to phagocytosed ... Fluid Testing: • WBCs ... gout treatment; ... severe allergic reactions ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
have fever - ACS ... , AKI, acute limb ... organ damage • Treatment ... Syndrome #TLS #diagnosis ... #management #hematology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
culture used to diagnose ... A reaction to phagocytosed ... stain and culture- Diagnose ... Gout #Comparison #rheumatology ... #Diagnosis