15 results
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... leading to an allergic ... complexes bind ... histamine) into the blood ... #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE antibodies bind ... When the specific allergen ... - Red blood cell ... with mismatched blood ... Classification #Pathophysiology
Causes of B12 deficiency. 

This great diagram shows normal absorption and outlines most possible causes. At
Causes of B12 deficiency ... releasing Cbl to bind ... transported into the blood ... transcobalamin (TC) bind ... #Diagnosis #Pathophysiology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... eosinophilia (common causes ... are asthma, allergy ... Differential #diagnosis #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... released during an allergic ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... Transfusing blood ... Blood saves lives ... unnecessary and cause ... Transfusion #Thresholds #Hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
of high parity blood ... donor • Pathophysiology ... without other cause ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology
COVID-19 - How does it affect you? 
Gas Exchange 
Each sac of air, or alveolus, is
capillaries where red blood ... that the oxygen passes ... the coronavirus bind ... azuravesta #COVID19 #Pathophysiology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... anemia • Sputum/Blood ... of PCN allergy ... #differential #causes
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Allergic ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology