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diagnosis hematology management differential product reactions transfusion algorithm anemia classification diffuse hodgkins lad leukemia lymphadenopathy lymphoma mds myelodysplasia myelodysplastic neutropenia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... result from low blood ... #Anemia #oncology ... #hematology #diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Infectious • EBV ... • Acne • Allergy ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... Transfusing blood ... Blood saves lives ... unnecessary and cause ... /vmoitra) #EBM
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... • Anemia • Aplastic ... #oncology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Allergic ... Causes purpura & ... TRALI): Leading cause ... due to marrow aplasia ... more likely to cause
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Allergic reaction ... Causes purpura & ... TRALI): Leading cause ... due to marrow aplasia ... diagnosis #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... • Cytopenia -> BM ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... CANDLE syndrome - Allergic ... neutrophils in the blood ... Syndrome #diagnosis #dermatology ... #oncology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
replacing the BM ... replacing the BM-common ... including white blood ... cell aplasia DOI ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Workup: • Full Blood ... marrow biopsy - if blood ... classification #hematology ... #oncology #management
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