12 results
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Cutaneous Drug Reactions ... IgE-mediated reactions ... T-cell-mediated reactions ... #dermatology #clinical ... #comparison #classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... lgM antibodies bind ... Acute transfusion reaction ... hypersensitivity #reactions ... allergy #table #classification
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
• Transfusion reactions ... Diagnosis #causes #classification ... #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... blood donor • Pathophysiology ... transfusion • Pathophysiology ... #Transfusion #Reactions ... #hematology #diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE antibodies bind ... Hypersensitivity #Types #Classification ... #Pathophysiology ... Allergy #Diagnosis #Reactions
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... to an allergic reaction ... Allergen-antibody complexes bind ... Allergy #Immunology #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
When antigens bind ... antibody-mediated immune reaction ... Allergy #Immunology #pathophysiology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... to an allergic reaction ... causes an immune reaction ... to an allergic reaction ... #Types #Classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #Hematology #Diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activity that bind ... diagnosis #types #classification ... #rheumatology #