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diagnosis management differential lfts laboratory syndrome transfusion algorithm chemistry cirrhosis interpretation oncology product tests workup abnormal activation aflp alkaline alkphos
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... Phosphatase and Bilirubin ... mitochondria (mAST ... initial insult Bilirubin ... #Hepatology #Pathophysiology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
hepatocellular injury • Bilirubin ... week • Direct bilirubin ... Elevation: • Bilirubin ... intestines, White blood ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... week • Direct bilirubin ... Elevation: • Bilirubin ... intestines, white blood ... diagnosis #algorithm #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
aminotransferase (ALT ... brain, heart, blood ... in bone Total bilirubin ... Indirect bilirubin ... Interpretation #diagnosis #hepatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
AIHA, Transfusion reactions ... Defects, Drugs, Liver ... - Peripheral Blood ... - Unconjugated Bilirubin ... Differential #Diagnosis #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... function similarly to mast ... during an allergic reaction ... Or Inflammatory Reactions ... #hematology #basophils
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... ) Pathophysiology ... = nonspecific (nausea ... Pregnancy #hepatology ... diagnosis #management #pathophysiology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
and unconjugated bilirubin ... and excretion of bilirubin ... disease, ALT and ... chronic anemia; blood ... LiverFailure #Hepatic #Hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
plateletcount), peripheral blood ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... not required in all ... #Workup #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
blood tests. ... blood tests, synthetic ... ALP, alkaline phosphatase ... aminotransferase; BMI, body mass ... Abnormal #Algorithm #Hepatology
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