20 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic #differential ... #Diagnosis #Management ... #gastroenterology ... #hepatology
Fontan-Associated Liver Disease

By Dr. Andrew Yu @michaelandrewyu via @EmoryGastroHep

#FALD #Fontan #Associated #Liver #Disease #gastroenterology #hepatology #pathophysiology
Fontan-Associated Liver ... Fontan #Associated #Liver ... #Disease #gastroenterology ... #hepatology #pathophysiology ... #diagnosis #management
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Hepatitis Procedures Management ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Hyperbilirubinemia - Differential ... MRCP, ERCP, liver ... direct #bilirubin #Differential ... Diagnosis #Algorithm #gastroenterology ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... infiltration) Differential ... #Pregnancy #hepatology ... obgyn #diagnosis #management ... #pathophysiology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... AIHA, Transfusion reactions ... Defects, Drugs, Liver ... #Hemolysis #Differential ... #Diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... Extrinsic Causes: • Liver ... • Transfusion reactions ... Hemolytic #Anemia #Differential ... classification #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... deficiency • Liver ... fever • Drug reactions ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
symptoms, elevated liver ... A liver biopsy can ... and hematologic ... algorithm #diagnosis #management ... #hepatology #gastroenterology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... common immune reaction ... eruptions, diarrhea, liver ... Transfusion #diagnosis #management ... #hematology #reactions