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diagnosis differential dermatology management clinical algorithm oncology physicalexam disease erythematosus systemic causes rash sle vasculitis ana antinuclear phenomenon raynauds treatment
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Kawasaki, Nephrotic syndrome ... , POEMS • Reaction ... Exercise, Allergic reactions ... Diagnosis #Algorithm #hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Raynaud's Phenomenon on Physical Exam #Raynauds #Syndrome #disease #phenomenon #clinical #video #physicalexam #fingers #hands #rheumatology
#Raynauds #Syndrome ... phenomenon #clinical #video ... fingers #hands #rheumatology
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 Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... glycoprotein I (ß2GP), Lupus ... LAC) • Sjogren Syndrome ... Autoantibodies #Rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Homogeneous: Systemic lupus ... , Drug-induced Lupus ... Speckled: Systemic lupus ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... block • Sjogren syndrome ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... Other: Transfusion reaction ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Vesiculobullous Skin ... Bullous impetigo - Reaction ... Bullous systemic lupus ... diabeticorum) - Reaction ... Vesiculobullous #SkinRash #dermatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... fever • Drug reactions ... Differential #Diagnosis #hematology ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Sjögrens (15%) Skin ... Demyelinating syndromes ... Thrombocytopenia #Lupus ... symptoms #diagnosis #rheumatology
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