21 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type 1 ... S - Systemic Lupus ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... typically prolong PT too ... Reduced liver synthesis ... #diagnosis #differential ... #hematology #coagulation
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Diagnosis Hepatocellular ... #Differential #Diagnosis ... #Causes #Acute ... #algorithm #hepatology
Approach to Neonatal Jaundice

Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Neonatal Jaundice Causes ... classified as due to (1) ... #Diagnosis #Peds ... #Jaundice #Algorithm ... #Differential #Workup
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
- Differential Diagnosis ... Algorithm 1. ... non-ICU vs ICU causes ... MRCP, ERCP, liver ... #hepatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Age 20-40, F:M 9:1 ... • Immunologic Workup ... Positive in 60-80% of cases ... Erythematosus #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
, 4:1 to 1:1 F:M ... • Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... #diagnosis #management
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... 1. ... inhibitor (e.g. antiphospholipid ... • Reduced liver ... #hematology #coagulation
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... Step 1: In the patient ... and hematologic ... #diagnosis #management
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Antiphospholipid ... maternal chromosomal causes ... excluded Testing: • Lupus ... #Algorithm #diagnosis ... #hematology