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differential hematology causes cll leukemia management oncology thrombocytosis common comparison cvid erythrocytosis fever hemeonc hypogammaglobulinemia hypophosphatemia immunecompromised immunocompromised immunodeficiency immunology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... chemotherapy for low-risk disease ... #oncology #hematology ... #hemeonc #diagnosis
Hypophosphatemia - Differential Diagnosis Algorithm Transcellular Shift • Recovery From DKA • Refeeding Syndrome • Acute Respiratory
- Differential Diagnosis ... Algorithm Transcellular ... • Small bowel diarrhea ... Inflammatory Bowel Disease ... #Algorithm #endocrinology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... phenomenon CLL Diagnosis ... cells can indicate disease ... microglobulin Treatment ... #diagnosis #workup
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... disorders • Celiac disease ... effect following treatment ... #Hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
- Differential Diagnosis ... Algorithm Relative ... • Burns • Diarrhea ... #Algorithm #Causes ... #Hematology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
- Differential Diagnosis ... Algorithm Normal ... Panhypopituitarism Treatment ... Disease • GI ... #Algorithm #endocrinology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... Autoimmunity • Chronic ... • Infectious diarrhea ... Granulomatous lymphocytic ... Malignancies • Chronic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic ... #Algorithm #hematology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
- Differential Diagnosis ... biopsy demonstrates lymphocytes ... the mainstay of treatment ... frequent in men Chronic ... comparison #table #dermatology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Algorithm Structural ... • Periodontal Disease ... Bronchitis • Chronic ... Diarrhea • Giardia ... #Hematology
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