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diagnosis differential causes hepatology management anemia arthritis injury approach blood classification joint mcv msk pain product reactions thrombocytosis workup aclf
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... disease, liver ... (DILI) Viral Hepatitis ... #Chronic #Liver ... Failure #Cirrhosis #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... , Acute biliary ... Syndrome, Celiac Disease ... , Infiltrative Disease ... #algorithm #hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... Infectious: • Acute ... or Chronic Inflammatory ... disorders • Celiac disease ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... → Refer to hematology ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... Renal Disease, Liver ... Reticulocytosis • Liver ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • NASH, Chronic ... injury: > 3 • Chronic ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ... dechallenge • Acute ... hepatitis fibrosis ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... disease: > 2 ... • NASH, Chronic ... injury: > 3 • Chronic ... #differential #Hepatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
) • Advanced Liver ... Disease - Alcohol ... , Viral hepatitis ... catastrophes, Acute ... comparison #diagnosis #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Differential Diagnosis Algorithm ... Tuberculosis • Hepatitis ... Fatigue • Acute ... Age > 50 • Chronic ... #Causes #Hematology
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