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diagnosis differential causes liver management hepatitis injury anemia classification oncology thrombocytosis aclf aih approach autoimmune cancer chemistry cirrhosis cll dili
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... Infectious: • Acute ... disorders • Celiac disease ... effect following treatment ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic ... #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Failure Infections Alcohol-Associated ... Failure #Cirrhosis #Hepatology
Hypophosphatemia - Differential Diagnosis Algorithm Transcellular Shift • Recovery From DKA • Refeeding Syndrome • Acute Respiratory
Differential Diagnosis Algorithm ... Refeeding Syndrome • Acute ... • Small bowel diarrhea ... Alcoholism Decreased ... Inflammatory Bowel Disease
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... HSV • Toxic: Alcohol ... Syndrome, Celiac Disease ... Medication, Pregnancy, Alcoholic ... #algorithm #hepatology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
kidney disease, ... Acute blood loss ... use, Liver disease ... independent of alcohol ... diagnosis #causes #hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Differential Diagnosis Algorithm ... • Burns • Diarrhea ... Smoking, Snoring Chronic ... Sleep Apnea • Chronic ... #Causes #Hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... liver disease, ... dechallenge • Acute ... #hepatology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Blood Loss • Acute ... RBCs on Smear • Chronic ... Disease • Marrow ... #Causes #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
screening for disease ... - Acute Bleeding ... Chronic Management ... Avoid meds that ... #hematology
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