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diagnosis hematology algorithm pancytopenia causes deficiency infections infectiousdiseases workup agglutinin aids bariatric bypass cold common copper cvid deficiencies elevatedmcv ferritin
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
, Chronic diarrhoea ... , Short bowel syndrome ... • Nutritional: ... Musculoskeletal: Low ... Haematological: Anaemia
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Production - Flow ... HLH syndrome 5. ... Drugs Nutritional ... Acquired Aplastic Anemia ... Metastatic Disease
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Vitamin D - Bone disease ... ataxia), Korsakoff syndrome ... immune function, diarrhea ... Bypass #vitamin #nutrition ... #table #differential
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... #Diagnosis #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Production - Flow ... HLH syndrome 5 ... Drugs Nutritional ... Acquired Aplastic Anemia ... Metastatic Disease
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... • Pancreatic Disease ... Myelodysplastic Syndromes ... • Liver Disease ... Algorithm #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Approach - MCV) Low ... chronic kidney disease ... Myelodysplastic syndrome ... morphologic #mcv #differential ... diagnosis #causes #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... - Differential ... Gastrectomy, WHDA syndrome ... Structural: Celiac disease ... Pregnancy, Lactation, Low
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
initiation of nutrition ... due to chronic disease ... Palpitations • Diarrhea ... , K, Mg2+) • Slow ... #Nutrition #Differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Infectious diarrhea ... autoimmune hemolytic anemia ... 300 mg/dL) • Low ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
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