57 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... • Autoimmune diseases ... Adult-onset Still disease ... Treatment: • ... #management #treatment
Causes of Acute Onset Fever - Differential Diagnosis Algorithm
Viral:
 • Rhinovirus
 • Influenza Virus
 • Parainfluenza
Causes of Acute ... Diagnosis Algorithm ... Bacteremia Septic Shock ... • Sickle Cell disease ... #Algorithm #causes
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... can mimic common infections ... following: • Fever ... • Bicytopenia Treatment ... : • Infection
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... Infections 2. ... symptoms - Headache, fever ... abdominal pain, diarrhea ... , Hypotension, shock
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
, Cough • +/-Nausea ... , vomiting, diarrhea ... cæxist with other infections ... - Fever lasting ... #management #treatment
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
- Differential Diagnosis ... Drugs • ICP / Infections ... blocking agent • Shock ... Cimetidine Infections ... #causes #cardiology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... - Differential Diagnosis ... Bacteremia/Septic Shock ... • Periodontal Disease ... Bronchitis • Chronic Diarrhea
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
common route of infection ... • Prodrome: fever ... , weakness +/- diarrhea ... Diagnosis: ... #management #treatment
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
of invasive GAS disease ... GAS in 30% of cases ... 50% in nec fasc Diagnostic ... day 2 + 3 BIDMC Infectious ... Diseases Fellowship
Travel History - Clues to Infectious Disease Diagnosis in a Traveler 
 • Where did you
Travel History - Clues ... to Infectious Disease ... Diagnosis in a ... → Travelers' diarrhea ... Rabies, cat scratch fever