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diagnosis differential dermatology nephrology oncology secondary systemic generalized hypophosphatemia pruritus thrombocytosis abdominal anemia cll diarrhea diffuse dili druginduced endocrinology eosinophilia
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Myelogenous Leukemia ... • Primary Myelofibrosis ... Infectious: • Acute ... #Causes #Hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... Myeloproliferative Disorder • Chronic ... myelogenous leukemia ... Polycythemia vera Acute ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Fatigue • Acute ... Age > 50 • Chronic ... #Causes #Hematology
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Differential Diagnosis Algorithm ... Primary - Over-production ... of nucleotides Primary ... (ALL) • Acute ... endocrinology #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... Chronic leukemia ... -> AML: Blast crises ... + distinctive primary ... #Hematology #Oncology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute ... Post-splenectomy Primary ... myeloid leukemia ... #hematology #secondary
Primary Dermatologic Nail Disorders - Differential Diagnosis Algorithm Nail Plate - Pitting • Psoriasis • Alopecia Areata Nail
Primary Dermatologic ... Trauma/lnfection - Acute ... Paronychia • Chronic ... Telangiectasia • SLE ... #causes
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... leukemia Measure ... Malabsorption, Chronic ... diarrhea, Poor ... Normal or High PTH: Primary
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Reticulocytosis • Primary ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Causes == Primary ... Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... #causes
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