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diagnosis differential rheumatology dermatology signs classification management manifestations skinrash symptoms syndrome behcet clinical complications cryoglobulinemia cryoglobulins dermpath disease feet legs
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
: CTD: SLE, RA related ... Hemorrhagic bullae, Ulceration ... nodules, Deep ulcers ... racemosa, Digital ulceration ... #dermatology #rheumatology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
insufficiency • Vasculitis ... Mycosis fungoides (cutaneous ... • Bleomycin Hematologic ... #ulcerative #skinrash ... #causes
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Vasculitis ... Identification of causes ... vasculitis • ... disease (10%) : SLE ... +++ • IgA vasculitis
Skin Ulcers of the Lower Legs / Feet - Differential Diagnosis Algorithm Physical: • Pressure • Trauma • Radiation Vascular: • Arterial
Skin Ulcers of the ... insufficiency • Vasculitis ... #ulcerative #skinrash ... #dermatology #Differential ... #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... livedo reticularis, ulcers ... genital aphthous ulcers ... , cutaneous, ocular ... , and SLE) • Urinalysis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... panuveitis, retinal vasculitis ... ) • Cutaneous Lesions ... MCC-small vessel vasculitis ... Oral aphthae : SLE
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Purpura - Skin ulcers ... • IgA vasculitis ... small-vessel vasculitis ... • Vasculitis ... #vasculitis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Autoimmune • ITP • SLE ... HUS • DIC • Vasculitis ... #Causes #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... Strong sign of cutaneous ... tract, and often causes ... , cutaneous, ocular
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... response -> Subacute cutaneous ... hair follicles -> causes ... > Mouth, Nasal Ulcers ... Livedo Reticularis, Vasculitis
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