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diagnosis rheumatology differential lupus management complications disease pathophysiology algorithm arthritis autoantibodies behcet causes classification cord disorders gastrointestinal laboratory manifestations mimickers
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Butterfly rash, Vasculitis ... Aseptic necrosis of hip ... #systemic #erythematosus ... #signs #symptoms
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... #SLE #Gastrointestinal ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Normal CK - Myositis ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... (SLE) - Typical ... Signs/Symptoms ... Arthralgia / arthritis, Myositis ... #SLE #Signs #Symptoms
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... anemia 4% - Myositis ... #Erythematosus ... autoantibodies #signs ... #symptoms #mimickers
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
lupus erythematosus ... Symptoms (Sx) in ... purpura: strong sign ... , and SLE) • Urinalysis ... Cryoglobulins • HIV
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... autoimmune disorders (Systemic ... lupus erythematosus ... Manifestations #diagnosis #neurology ... #symptoms #signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ANCA-associated vasculitis ... • Transverse Myelitis ... Induced Lupus: • Symptoms ... #Systemic #Lupus
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
central nervous system ... Peripheral Nervous System ... Lack of UMN/LMN signs ... parainfluenza, Coxsackie, HIV ... Differential #Diagnosis #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Symptoms (SX) in ... purpura: Strong sign ... ischemia • Skin: Erythematous ... • Progressive symptoms
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