11 results
rheumatology management sle antibodies antinuclear arthritis dermatology differential algorithm anca antimda5 antimda5dm antineutrophil antinxp2 antinxp2dm antiphospholipid apls approach classification clues
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... ) • Systemic lupus ... erythematosus ... dermatomyositis ... #antibodies #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... • Immunologic Workup ... : - ANA > ... #Summary #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antibody refers ... erythematosus ( ... , Polymyositis/Dermatomyositis ... #patterns #rheumatology ... #diagnosis #differential
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
: - ANA > ... Erythematosus ( ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
many differential diagnoses ... #diagnosis #sle ... #clues #system ... #erythematosus # ... rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Periorbital heliotrope (blue-purple ... with edema • Erythematous ... erythematous auricular ... #rheumatology # ... dermatology #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus ( ... (to support a diagnosis ... #diagnosis #testing
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
with edema • Erythematous ... erythematous auricular ... Muscle atrophy may cause ... levels • NXP-2 antibody ... : • ILD was diagnosed
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... cytoplasmic antibody ... (e.g. systemic lupus ... erythematosus (
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup ... chromosomal causes ... excluded Testing: • Lupus ... #Algorithm #diagnosis ... #hematology
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