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diagnosis management clinical differential pharmacology algorithm treatment causes pocus infectiousdiseases cardiology microbiology echocardiogram infections bacteria table idsa photo dermatology overview
Daptomycin - Antibiotics Class Overview Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... Mechanism: Lipopeptide antibiotic ... more for MRSA bacteremia ... /endocarditis (due ... #Pharmacology #Antibiotics
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
start empiric antibiotics ... Antibiotic Management ... Persistent fever and/or bacteremia ... metastatic infection (endocarditis ... Persistent fever and/or bacteremia
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
with Infective Endocarditis ... Did they receive antibiotics ... Decreased yield due to antibiotic ... have a fastidious bacteria ... #Infective #Endocarditis
Infective endocarditis - etiology and sources of infection. • Native and prosthetic valve endocarditis •
Infective endocarditis ... prosthetic valve endocarditis ... for TPN) and antibiotic ... #Infective #Endocarditis ... Sources #Causes #Bacteria
Aminoglycosides - Antibiotics Class Overview Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV) Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... suspected (pneumonia, bacteremia ... effect (mainly in endocarditis ... #Pharmacology #Antibiotics
Synercid (Quinupristin/Dalfopristin) (IV) - Antibiotics Class Overview Mechanism: “Streptogramins”– inhibits sequential steps in ribosomal synthesis Spectrum: covers MRSA
Dalfopristin) (IV) - Antibiotics ... Poor choice for bacteremia ... /endocarditis due ... #Pharmacology #Antibiotics
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Bug: Atypical bacteria ... Aggressive: MRSA bacteremia ... Treatment: • Antibiotic ... lines, osteo, endocarditis
Spinal Epidural Abscess - Illness Script Epidemiology: - Patients at risk for bacteremia: IVDU, dental abscess, HD
Patients at risk for bacteremia ... , HD catheter, endocarditis ... Surgical drainage - Antibiotics
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Endocarditis Summary ... Prosthetic Valve Endocarditis ... • IV Antibiotics ... • Persistent bacteremia ... #Endocarditis
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Endocarditis - Overview ... Prosthetic Valve Endocarditis ... Treatment • IV antibiotics ... • Persistent bacteremia ... #Endocarditis
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