2222 results
Lower Urinary Tract Infections: Complications
 - Infection damages the urinary tract epithelium causing fibroblast proliferation and
Urinary Tract Infections ... epithelial barrier -> Bacteria ... - In males, bacteria ... Urease-producing bacteria ... UrinaryTractInfection #LUTI #Pathophysiology
Lemierre’s Syndrome - Pathophysiology

Lemierre’s is an infectious thrombophlebitis of the internal jugular vein.

 - It starts
Lemierre’s Syndrome - Pathophysiology ... Lemierre’s is an infectious ... oropharyngeal infection ... patient becomes bacteremic ... Lemierres #Syndrome #Pathophysiology
Non-Infective Endocarditis - Pathophysiology
Non-infective Endocarditis Pathophysiology:
 • Valves usually undamaged - Etiology poorly understood but thought
Endocarditis - Pathophysiology ... Non-infective Endocarditis Pathophysiology ... endothelium is common → Bacteria ... over clusters of bacteria ... and failure - Infectious
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
other gram (-) infections ... pathogens Bacterial infection ... => • Bacteria ... stiffness • Bacteria ... C5C9Deficiency #Complement #pathophysiology
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
Anaplasma Infection ... phagocytophilum Pathophysiology ... intracellular bacteria ... #Anaplasma #Infection
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
overlook severe infections ... culture proven bacteremia ... culture proven bacteremia ... culture proven bacteremia ... CBC #hematology #pathophysiology
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
Malformation) Infections ... Urease-producing bacteria ... loading) - Infections ... Differential #Diagnosis #Pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Triggering factor (infection ... Acquired HLH: • Infections ... CMV, HHV8,...), Bacteria ... Still disease, Infection
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
intracellular rod-shaped bacteria ... for 4.6% of new infections ... tuberculosis (LTBI) Pathophysiology ... Response: • Most bacteria ... lung disease, bacteremia
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
Urinary Tract Infection ... flow) - Fecal bacteria ... Urinary Tract Infection ... tract by capable bacteria ... UrinaryTractInfection #LUTI #Pathophysiology