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Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
Rigors And Bacteremia ... pathogen (e.g., bacteria ... PATHOPHYSIOLOGY: ... #Pathophysiology ... #InfectiousDiseases
Antibiotic Stewardship: Shorter is Better 
CAP 
HAP 
VAP 
Intra-abd 
Gram Neg Bacteremia 
AECB 
Cellulitis 
Osteo 
Septic
Intra-abd Gram Neg Bacteremia ... #Stewardship #InfectiousDiseases
Infective Endocarditis - Indications for Surgery - "Fun-HEARTS" Mnemonic

Fungal endocarditis
Heart failure (valve dysfunction)
Enterococcus (VRE) endocarditis
Abscess, annular
Time, sustained bacteremia ... cardiothoracic #cardiology #infectiousdiseases
Bacteremia Quick Reference - Treatment Duration

Gram Negative Bacteremia:
 • Avoid: Aminoglycosides and tigecycline
 • Catheters should
Bacteremia Quick ... Gram Negative Bacteremia ... Gram Positive Bacteremia ... TheIDtrivia #Bacteremia ... Management #Duration #infectiousdiseases
Non-Infective Endocarditis - Pathophysiology
Non-infective Endocarditis Pathophysiology:
 • Valves usually undamaged - Etiology poorly understood but thought
Endocarditis - Pathophysiology ... Non-infective Endocarditis Pathophysiology ... endothelium is common → Bacteria ... over clusters of bacteria ... NBTE #Marantic #pathophysiology
Antibiogram - Antibiotic Resistance Table for Severe Multidrug Resistant Bacteria

ESBL Enterobacteriaceae
Carbapenem-Resistant Enterobacteriaceae
MDR Pseudomonas Aeruginosa
Carbapenem-Resistant Acinetobacter

Adapted from
Multidrug Resistant Bacteria ... Antibiotic #Resistance #InfectiousDiseases
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Pre-transplant: • Common bacteria ... Engraftment: • Common bacteria ... post-engraftment: • Bacteria ... diagnosis #causes #infectiousdiseases
HACEK is the acronym commonly used to describe and help doctors to remember a group of
caused by HACEK bacteria ... #Diagnosis #InfectiousDiseases
Antibiotic Stewardship: Shorter is Better
CAP 3-5d = 5-14d
VAP 8d = 15d
Intra-abd 5 or 7d = 10
10 or 14d GNB Bacteremia ... #Stewardship #InfectiousDiseases
Lower Urinary Tract Infections: Complications
 - Infection damages the urinary tract epithelium causing fibroblast proliferation and
epithelial barrier -> Bacteria ... - In males, bacteria ... Urease-producing bacteria ... UrinaryTractInfection #LUTI #Pathophysiology