31 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Viral Infection Clinical ... younger pts) Differential ... #anemia #hematology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
in a an oncology ... I - Infection: Bacterial ... Gangrenosum, NEH T - Treatment ... #oncology #differential ... MINTC #Mnemonic #dermatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... • Rheumatic disorders ... • Celiac disease ... effect following treatment ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... infections, TB, Acute bacterial ... Diagnosis #Algorithm #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... gangrenosum • Bacterial ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Splenomegaly - Differential ... Infectious • Bacterial ... Myeloproliferative disorders ... Spleen #Enlarged #Differential ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Agglutination - Cold agglutinins ... Consider RBC membrane disorder ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Lymphoproliferative disorders ... Myeloproliferative disorders ... thrombocythemia), Autoimmune disease ... Diagnosis #Management #treatment ... #hematology #differential
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... inherited bleeding disorder ... Clinical • ... factor VIII) Treatment ... #Diagnosis #Hematology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Treponema pallidum bacterial ... with or without treatment ... , but without treatment ... #Diagnosis #Clinical ... #Photo #Dermatology