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diagnosis symptoms signs differential management pharmacology cardiology endocrinology nephrology infectiousdiseases syndrome causes algorithm treatment clinical microbiology pulmonary complications msk ophthalmology
Purple Urine Bag Syndrome Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine Tryptophan → Indoxyl
indwelling catheter + bacteriuria ... Sulfatase enzyme (bacteria ... Syndrome #PUBS #pathophysiology
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
Rigors And Bacteremia ... pathogen (e.g., bacteria ... in identifying bacteremia ... PATHOPHYSIOLOGY: ... #Pathophysiology
Non-Infective Endocarditis - Pathophysiology Non-infective Endocarditis Pathophysiology: • Valves usually undamaged - Etiology poorly understood but thought
Endocarditis - Pathophysiology ... Non-infective Endocarditis Pathophysiology ... endothelium is common → Bacteria ... over clusters of bacteria ... NBTE #Marantic #pathophysiology
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings Predisposing Factors: - Immunocompromised, Diabetes, - Elderly, Female
Infection (LUTI) -> Bacteria ... of asymptomatic bacteriuria ... UrinaryTractInfection #UUTI #Pathophysiology
Lower Urinary Tract Infections: Complications - Infection damages the urinary tract epithelium causing fibroblast proliferation and
epithelial barrier -> Bacteria ... - In males, bacteria ... Urease-producing bacteria ... UrinaryTractInfection #LUTI #Pathophysiology
Gonorrhea: Pathophysiology - Neonatal Transmission -> Direct contact of patient mucosa with mother's infected mucosa while
Gonorrhea: Pathophysiology ... Immediate transfer of bacteria ... cell surface -> Bacteria ... proteins and LPS on bacteria ... #Gonorrhea #Pathophysiology
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
susceptibility to bacteremia ... => • Bacteria ... stiffness • Bacteria ... C5C9Deficiency #Complement #pathophysiology
Metabolic Pathways of Purple Urine Bag Syndrome: Adopted from chart originally published in Purple Urine Bag
Bacteria commonly ... #Pathophysiology
Anaplasma Infection - Anaplasma phagocytophilum Pathophysiology: • Obligate, intracellular bacteria • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... intracellular bacteria
Fever - Pyrogen Pathophysiology EXOGENOUS PYROGEN • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins •
Fever - Pyrogen Pathophysiology ... EXOGENOUS PYROGEN • Bacteria ... Fever #Fever #Pathophysiology
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