29 results
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... → Sickle Cell anemia ... anemia (TTP, HUS ... #Anemia #Differential ... #causes
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
of anemia include ... Diagnosis: • hemolytic ... anemia • Cold ... IgM) • Blood smear ... #anemia #hematology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... anaemia, ataxia ... paraesthesiae • Folate - Anaemia ... Vitamin B12 - Anaemia ... #signs #symptoms
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
within morulae Signs ... and symptoms: ... after bite • Fever ... immature forms) • Anemia ... Anaplasma #Infection #diagnosis
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
disease caused ... Lutzomyia verrucarum Clinical ... lysis → severe hemolytic ... anemia, jaundice ... phase: Peripheral smear
Arrhythmias - Differential Diagnosis Algorithm
May present as: palpitations, dizziness, syncope, chest discomfort
Cardiac Causes:
 - Structural
- Differential Diagnosis ... tissue (previous MI ... State: • Anemia ... • Fever/infection ... #Arrhythmias #Cardiology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... (SLE) General: Fever ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Malar rash 40% - Fever ... Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... autoantibodies #signs ... #symptoms #mimickers
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Clinical Presentation ... and petechiae Causes ... • Improve the symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs ... years - May have signs ... : - MRI is modality ... Detection of AFB by smear