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diagnosis differential hematology causes management algorithm nutrition clinical hemolytic oncology signs symptoms blood bloodsmear classification path rheumatology vitaminb12 hemolysis hepatology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Megaloblastic Anemia ... Microangiopathic hemolytic anemia ... Autoimmune hemolytic anemia ... Bite cells: G6PD deficiency ... interpretation #clinical #anemia
Elliptocyte - Note the shape of these appropriately named erythrocytes. In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... and severe iron deficiency ... anemia. ... BloodSmear #Blood #Smear
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic Anemia ... (AIHA) Pathophysiology ... or negative - Smear ... Autoimmune #Hemolytic #Anemia ... #Pathophysiology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Normochromic RBCs on Smear ... • Aplastic Anemia ... • Anemia of Chronic ... Non-lmmune #Anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
anemia, Thalassemia ... Sideroblastic anemia ... Megaloblastic anemia ... Myelodysplastic syndrome ... Hemolytic uremic syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Normal Blood Smear ... • Pernicious Anemia ... • Pernicious Anemia ... #Macrocytic #Anemia
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
peripheral blood smear ... changes with iron deficiency ... anemia. ... PeripheralBloodSmear #BloodSmear #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Peripheral blood smear ... DAT (-) → G6PD Deficiency ... → Sickle Cell anemia ... Microangiopathic hemolytic anemia
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... thalassemia • Anemia ... Normocytic" • Anemia ... Acute blood loss, Anemia ... Myelodysplastic syndrome
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... C3d • Blood smear ... Autoimmune #Hemolytic #Anemia ... diagnosis #management #treatment
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