97 results
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Anemia #Aplastic ... #Anemia #Causes ... #Pathophysiology ... #Pathology #Treatment ... #Management #Differential
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... • Anemia: macrocytic ... C3d • Blood smear ... : Differential → ... Autoimmune #Hemolytic #Anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Deficiency • Aplastic Anemia ... • Anemia of Chronic ... Non-lmmune #Anemia ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Normal Blood Smear ... • Pernicious Anemia ... • Pernicious Anemia ... #Macrocytic #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Peripheral blood smear ... → Sickle Cell anemia ... Microangiopathic hemolytic anemia ... #causes
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
for Anemia (Morphological ... thalassemia • Anemia ... Myelodysplastic syndrome ... morphologic #mcv #differential ... #diagnosis #causes
Causes of Depressed / Lethargic Newborn - Differential Diagnosis Algorithm
Maternal Related:
 • Drugs (Ex. SSRI)
 •
Causes of Depressed ... Diagnosis Algorithm ... Respiratory Distress Syndrome ... Sepsis Other: • Anemia ... #Causes #Peds #
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
• chronic anæmia ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential ... #Causes #Diagnosis
Gastrointestinal Causes of Iron Deficiency Anemia
 • Mass lesions: Carcinoma, Large polyps
 • Inflammatory: Reflux esophagitis,
Iron Deficiency Anemia ... rubber bleb nevus syndrome ... Iron #Deficiency #Anemia ... #Causes #differential ... #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Anemia • Aplastic ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia