167 results
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... , Liver diseases ... cells - Renal diseases ... , Liver diseases ... , Pulmonary emboli
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... disease anemia ... B12 or Folate deficiency ... Cell RBC: G6PD deficiency
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... 80 fL) • Iron Deficiency ... of Chronic Disease ... 100 fL) • B12 Deficiency ... • Folate Deficiency
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Pregnancy, EPO treatment ... Loss (without anaemia ... Edema, Celiac disease ... • Inflammatory Disease
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
 - RDW, FEP, serum iron,
Iron Deficiency ... Anemia vs Anemia ... of Chronic Disease ... TIBC-specific for iron deficiency ... #Disease #Laboratory
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Iron Deficiency ... Anemia - Differential ... athletic training, Pulmonary ... Structural: Celiac disease ... #Anemia #Differential
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... Algorithm - Iron deficiency ... anemia - Anemia ... chronic kidney disease ... and/or folate deficiency
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell disease ... Cold agglutinins disease ... , Hemoglobin H disease ... ARUPLabs #Hemolytic #Anemia
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
inflammation) • Iron deficiency ... Sideroblastic anemia ... Megaloblastic: Folate deficiency ... , B12 deficiency ... Non-megaloblastic: Liver disease
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... autoinflammatory diseases ... mevalonate kinase deficiency ... hepatitis • Pulmonary ... diagnosis #management #treatment