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diagnosis lfts causes transaminitis hepatitis abnormal abscess acute bilirubin conjugated dili direct drug enzymes function hepatic hepatocellular hyperbilirubinemia idiosyncratic induced
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... #differential # ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... : • Genetic/Metabolic ... injury) • Ischemic ... #Tests #LFTs #Differential ... #Diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... #Injury #Differential ... #Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... NASH, Genetic / Metabolic ... #Injury #hepatology ... transaminitis #differential
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Diagnosis Algorithm ... MRCP, ERCP, liver ... #Diagnosis #Algorithm ... #gastroenterology ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... • Metabolic/Hereditary ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Injury - Differential ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
of Seizures - Differential ... Diagnosis Algorithm ... Traumatic brain injury ... Neurocysticercosis, PML • Metabolic ... Hypoxia, Uremia, Liver
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
Pericarditis - Differential ... Diagnosis Algorithm ... • Post-cardiac injury ... • Dissection Metabolic ... #Causes #Cardiology
Liver Abscess Differential Diagnostic Algorithm #Hepatic #Liver #Abscess #Infection #Diagnosis #Algorithm #Radiology #Differential #Hepatology
Liver Abscess Differential ... Diagnostic Algorithm ... #Hepatic #Liver ... #Radiology #Differential ... #Hepatology
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