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diagnosis hematology oncology hemophagocytic lymphohistiocytosis hemeonc syndrome blood chronic cll leukemia lymphocytic mds myelodysplastic product reactions activation algorithm anemia anesthesia
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
can mimic common infections ... • Bicytopenia Treatment ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... /µL Workup • Screen ... drug reaction, infection ... Strongyloides infection ... glucocorticoid treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... = funny-shaped cells ... risk-stratification • Risks: infection ... only curative treatment ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... associated with infection ... autoimmune disease, treatment ... #Treatment #management ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Anterior Non-necrotizing Scleritis - Slit Lamp Ocular Examination This 57 yo WM reported to clinic complaining of
patient was sent to rheumatology ... further systemic workup ... and treatment. ... Scleritis #clinical #video ... #physicalexam #rheumatology
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 Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Triggers: ▪ Infections ... Treatment Approach ... underlying trigger: Infections ... #Hematology #HemeOnc
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
increased IgG4+ cells ... " Treatment: ... Disease #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
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